Overview

The Associate Director, Feasibility Center of Excellence (CoE) is responsible for leading predictable and competitive delivery of indication, program, study, country, and site levels of feasibility. The Associate Director collaborates cross-functionally to improve processes, optimize protocols, improve predictive enrollment through data driving strategies for selecting sites and countries and supports feasibility adoption. This role emphasizes leadership, operational excellence, patient-centered design, and data innovation.

Key Responsibilities

Feasibility Leadership & Oversight

• Lead the operational delivery of feasibility assessments across a portfolio of clinical trials, from early planning through site selection.
• Ensure timely and high-quality feasibility deliverables that inform protocol design, geographic strategy, protocol optimization, and enrollment forecasting.
• Lead as an expert and primary point of contact supporting global study leaders with protocol feasibility, complexity of scoring, site burden, and patient voice during the study planning phase.
• Collaborate with the Sr. Director to set clear goals, support resource planning, team structure, and functional excellence initiatives.
• Provide subject matter expertise and help establish and refine SOPs, work instructions, and best practices for the feasibility function.
• Monitor key performance indicators (KPIs) for feasibility and enrollment predictability across studies.
• Drive quality, consistency, and risk mitigation in feasibility deliverables across therapeutic areas and regions.

Cross-Functional Collaboration

• Partner closely with Clinical Operations, Clinical Science, Commercial, Study Start-Up, etc. to integrate feasibility insights into study planning.
• Coordinate with external partners (CROs, data vendors, consultants) for feasibility data sourcing and modeling support.
• Present feasibility findings and recommendations to cross-functional stakeholders and governance bodies.
• Champion a patient and site centric mindset to ensure protocol design and patient eligibility.

Data & Tool Utilization

• Leverage a wide range of internal and external data sources to inform feasibility assessments, including RWD/RWE, site metrics, epidemiology, and historic trial performance.
• Promote the use of digital tools, predictive analytics, and AI-driven platforms in feasibility forecasting and modeling.
• Contribute to the continuous improvement of feasibility templates, dashboards, and methodologies.
• Support the adoption of data-driven methodologies and technologies (data analytics, competitive intelligence, and country specific insights)
• Monitor, support, and report feasibility KPIs, benchmarks, and insights for leadership.

Qualifications

Education

• Bachelor’s Degree in Life Science or related discipline (Master's degree or higher preferred)

Experience

• Minimum 8 years of experience in clinical research, feasibility, or clinical operations within a pharmaceutical, biotech, or CRO setting.
• Minimum 1-2 years of feasibility-focused role.
• Demonstrated ability to lead end-to-end feasibility assessments across multiple studies and/or indications.
• Deep knowledge of clinical trial design, patient recruitment challenges, and global study execution.
• Proficiency with feasibility data sources and tools, and data interpretation skills; familiarity with tools like CTMS, Citeline, IQVIA, RWD sources, and feasibility modeling platforms.
• Excellent leadership, communication, and interpersonal skills.
• Strategic thinker with strong project management and organizational abilities.
• Demonstrated ability to influence, collaborate, and lead change across a complex matrixed environment.
• Willingness to travel up to 10%, including international as required

#LI-AL1 #LI-Remote

U.S. Pay Range

$165,800.00 - $224,200.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.