• Establish and manage site relationships, including but not limited to: Act as liaison between the company and investigational sites, building investigator and site staff awareness on client compounds • Develop and implement a plan, in collaboration with global and local teams, to raise the profile of the company and its global clinical development projects with current and potential investigators • Independently perform activities associated with the evaluation of investigational sites to build company network • Proactively work with Medical/Patient/Industry Associations to build company network and to promote company clinical trials • Develop knowledge of site capabilities and past performance to assess their potential as participating sites in client clinical trials • Ensure regular communication with local organization to align interactions with KTLs and other relevant local/regional stakeholders • Oversee site-level study start-up, conduct, and close-out activities outsourced to CRO(s) for global programs across Therapeutic Areas, including but not limited to: Support Site Agreement negotiations, including stand-alone and Master Site Agreements • Identify trends, issues and risks across sites, and work with external vendors and internal Trial Team to resolve/mitigate those • Collaborate with external vendors and internal Trial Team, to ensure that sites are activated in a timely manner and according to agreed timelines • Collaborate with external vendors and internal Trial Team, to ensure that sites deliver on expected recruitment targets, including identifying reasons for non-recruitment, and identification of non-performing sites that require actions • Ensure ICH/GCP/local regulatory requirements are observed • Provide documented sponsor site oversight at country level for outsourced trials in country under remit as required by regulation • Utilize site performance and quality data to optimize prioritization of oversight actions