Liquidia is deeply passionate and committed to the discovery, engineering, and development required to bring novel therapies to patients who need them most, and to the healthcare providers who care for them. Our current drive is toward improving the treatment of pulmonary hypertension (PH). We will continue to combine our proprietary, innovative PRINT® Technology with new and established medications, offering the potential for both better precision and improved clinical outcomes. Our team members include some of the industry’s top scientists, clinicians, business strategists, engineers, and pharmaceutical executives. We work together to help people lead longer, healthier, and happier lives.

Job Summary
The Senior Medical Director, Cardiorespiratory Clinical Development, will serve as the scientific and clinical lead for programs advancing novel therapies targeting cardiovascular and pulmonary diseases. This position will guide development activities from first-in-human (Phase I) through late-stage (Phase IV) clinical trials.

The ideal candidate is a PhD-trained translational or clinical scientist with deep expertise in cardiorespiratory physiology, pulmonary hypertension, heart failure, or related pathophysiology, and a proven track record supporting clinical development in the biotechnology or pharmaceutical industry. This role requires both strategic vision and hands-on leadership, working cross-functionally to bring innovative therapies from bench to bedside. Education

• For Non-MD position: PharmD or PhDin a relevant biomedical field (e.g., physiology, pharmacology, molecular biology, or related discipline).
• For MD or DO: MD or DO with strong clinical trial experience in cardiovascular or pulmonary disease and preferably board certified (or equivalent) in respiratory medicine, cardiology or cardiovascular medicine.

Experience

• 15+ years of clinical research experience in the biopharmaceutical industry, including direct involvement in Phase I–IV studies.
• Demonstrated expertise in cardiovascular or pulmonary drug development, including conditions such as pulmonary hypertension, heart failure, COPD or fibrosis.
• Experience with clinical pharmacology, biomarker-driven development, or translational medicine preferred.
• Proven ability to contribute to regulatory filings and agency interactions.

Skills and Attributes

• Strong grasp of cardiorespiratory pathophysiology and clinical trial design principles.
  
• Exceptional communication and presentation skills, able to distill complex scientific data into actionable insights.
  
• Collaborative, flexible, and entrepreneurial mindset suited to a small-company culture.
  
• Demonstrated leadership and cross-functional influence in matrixed environments.

Location/Travel

• This position is remote or office-based, depending on location. Travel may be required as needed to support the assigned clinical trial/s but would not be expected to exceed 30%.  

Clinical Development & Study Oversight

• Provide medical and scientific leadership across cardiorespiratory development programs (Phase I–IV).
• Design and review clinical trial protocols, investigator brochures, and clinical study reports to ensure robust scientific rationale and regulatory compliance.
• Lead clinical interpretation of efficacy, safety, and biomarker data, ensuring integration with preclinical and translational findings.
• Oversee medical monitoring during trials, including review of adverse events and emerging safety signals.
• Oversee and support investigator led or supported studies 
• Collaborate closely with Clinical Operations, Biostatistics, and Regulatory Affairs to ensure efficient study execution and data integrity.

Strategic Program Leadership

• Contribute to the clinical development plan (CDP) and overall regulatory strategy for cardiorespiratory assets.
• Identify novel clinical endpoints, biomarkers, and imaging modalities relevant to cardiopulmonary physiology.
• Support translational integration between preclinical pharmacology, biomarker discovery, and clinical outcomes.
• Provide scientific input into target product profiles, risk–benefit assessments and go/no-go decisions.

Cross-functional and External Collaboration

• Serve as a medical and scientific resource for internal teams including discovery, regulatory, safety, and medical affairs.
• Build and maintain relationships with key opinion leaders (KOLs) in cardiology, pulmonology, and respiratory medicine.
• Represent the company at advisory boards, scientific congresses, and regulatory agency meetings.
• Support scientific publications, abstracts, and presentations related to the company’s clinical programs.

Regulatory and Compliance

• Partner with Regulatory Affairs to contribute to IND, CTA, NDA, and BLA submissions.
• Ensure compliance with ICH-GCP, FDA, and EMA standards.
• Participate in data monitoring committees and internal safety reviews as needed.

Liquidia offers a competitive compensation package as well as a comprehensive benefits package that includes Medical, Dental, Vision, STD, LTD, 401(k) Savings Retirement Plan, ESPP, and more!

Liquidia is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. Reasonable accommodation may be made to enable qualified individuals with disabilities to perform the essential functions of this position.

Recruiting Agencies, Please Note:
Liquidia will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Liquidia via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Liquidia. No fee will be paid in the event the candidate is hired by Liquidia as a result of the referral or through other means.