Associate Scientific Director, Pharmacometrics

DirectorDirectorFull TimeRemoteTeam 5,001-10,000H1B SponsorCompany SiteLinkedIn

Location

United States

Posted

54 days ago

Salary

$167K - $230K / year

Postgraduate Degree5 yrs expEnglish

Job Description

• Provide pharmacometrics expertise to activities throughout the drug development lifecycle and effectively collaborate with cross functional teams • Execute advanced pharmacometrics analyses, with emphasis on PK/PD modeling and simulation and exposure-response analysis for high priority programs • Identify opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy and safety • Contribute to Model Informed Drug Development (MIDD) activities to support dose selection, regimen optimization and clinical trial design • Communicate the pharmacometrics analysis results to program teams to support data-driven decision-making process • Mentor and guide Clinical Pharmacology and Pharmacometrics colleagues on pharmacometrics analyses methodologies • Serve as a lead author and key contributor for pharmacometrics sections of clinical and regulatory documents • Publish in scientific journals and present at internal and external scientific events

Job Requirements

  • PhD in Pharmacology, Pharmacokinetics, Pharmaceutics or a related quantitative discipline.
  • 5+ years of relevant industry experience applying population PK/PD and other advanced quantitative methodologies to decision making.
  • Deep and extensive experience with advanced population PK/PD methodology
  • Strong understanding of the clinical pharmacology principles and methodologies and their application in drug development
  • Solid knowledge of the drug development process and regulatory expectations for pharmacometrics analyses
  • Ability to interpret quantitative results and translate analyses into actionable program insights
  • Hands-on experience with pharmacometrics software tools such as NONMEM, Monolix, and R.
  • Experience with mechanistic or systems pharmacology models is a plus.

Benefits

  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation

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