Evotec logo
Evotec

#researchneverstops

Head of Project Toxicology

Medical DirectorMedical DirectorFull TimeRemoteLeadTeam 5,001-10,000Since 1993H1B SponsorCompany SiteLinkedIn

Location

United States + 3 moreAll locations: United States, France, Italy, United Kingdom

Posted

2 days ago

Salary

Not specified

Seniority

Lead

No structured requirement data.

Job Description

 

Purpose of the role 

 

As the VP, Head of Project Toxicology, you will define and lead the safety assessment strategy across Evotec drug discovery and development portfolio, ensuring robust, science‑driven decision‑making from early concept through regulatory submission. Serving as the key interface between discovery and development safety, you will shape the direction of our programs, strengthen strategic partnerships, and foster high‑impact collaboration across diverse modalities and therapeutic areas. You will lead and develop a high‑performing team of toxicology experts while working closely with senior leaders across the organisation and our global partners to deliver integrated, forward‑looking safety strategies. This role may be based at any of our global sites, with flexible working arrangements available. 

 

Core accountabilities 

 

  • Own and advance the organisation’s safety strategy for both internal programs and external partnerships, ensuring Evotec’s toxicology framework remains innovative, data‑driven, and scientifically robust. 

  • Inspire, mentor, and develop a team of expert toxicologists, providing strong scientific leadership, strategic direction, and a culture of continual learning. 

  • Provide pivotal support to Discovery teams across small‑ and large‑molecule programs, expertly guiding safety strategy from Target Safety Assessment through Development Candidate (DC) nomination. 

  • Serve as a trusted subject matter expert to Discovery and Development teams, enabling effective design, execution, and interpretation of regulatory toxicology studies in support of Phase 1 clinical trials and beyond. 

  • Build and maintain collaborative, trusted relationships with global clients, aligning on safety strategy and ensuring seamless, shared progress toward program objectives. 

  • Work closely with colleagues across internal functions to foster strong integration, transparent communication, and cohesive decision‑making across the portfolio. 

  • Model and cultivate a culture of ownership, trust, accountability, and empowerment across the team and broader organisation. 

 

We are an equal opportunities employer and welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation, or age. 

 

 

Capability, Knowledge and Experience:  

  • Extensive senior‑level experience in Toxicology, gained within biotech, pharma, and/or CRO environments, with a strong understanding of the strategic and operational demands of project‑driven organisations. 

  • Demonstrated leadership of interdisciplinary, cross‑functional teams, with the ability to influence, motivate, and align diverse scientific and operational groups within a complex matrix setting. 

  • Exceptional communication and scientific synthesis skills, capable of integrating complex data to deliver clear, actionable, and risk‑balanced recommendations to project teams, partners, and senior leadership. 

  • Proven track record of advancing programs from preclinical discovery into clinical development, across multiple modalities and therapeutic areas. 

  • Deep expertise in preclinical drug discovery models, with the ability to synthesise complex scientific strategies, navigate uncertainty, and align preclinical plans with development objectives. 

  • Highly skilled in managing challenging stakeholder dynamics, resolving conflict, and ensuring effective collaboration across discovery, clinical, regulatory, and operational functions. 

  • Demonstrated experience in preparing and contributing to successful IND/CTA submissions for both small‑molecule and biologic programs. 

  • Comprehensive knowledge of global regulatory safety guidelines, and their practical application across different modalities and therapeutic landscapes. 

  • Strong organisational and planning capabilities, with meticulous attention to detail and effective time‑management skills in a fast‑paced environment. 

  • Creative, strategic problem‑solver with a growth mindset, demonstrating adaptability, curiosity, and an openness to new approaches and emerging science. 

 

Education and Qualifications: 

  • BSc, MSc, or PhD in Toxicology, Pharmacology, Biology, or a related scientific discipline, with substantial relevant experience. 

  • DBAT, ERT, UKRT or equivalent professional certification is desirable 

 

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.

Related Categories

Related Job Pages

More Medical Director Jobs

Medical University of South Carolina logo

Virtual PRN Advanced Practice Provider (NP/PA) | MUSC Health Department of Emergency Medicine | Telehealth

Medical University of South Carolina

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees.

Medical Director2 days ago
Full TimeRemoteTeam 10,001

Providers will conduct virtual assessments and support the care of Emergency Department lobby patients across the health system, collaborating with on-site teams to relay critical information. A key focus is enhancing the patient experience through exceptional clinical care and outstanding customer service.

United States
Medical Director2 days ago
Full TimeRemoteTeam 501-1,000

The Medical Director collaborates with a DRG Integrity Specialist to review inpatient charts, ensuring clinical documentation accurately reflects patient acuity and complexity for appropriate coding and DRG assignment. Responsibilities include providing clinical leadership, generating compliant physician queries based on clinical indicators, and overseeing the quality of the assigned team's work.

United States
Part TimeRemote

We are recruiting board-certified or board-eligible radiologists with interest or experience in emergency and hospital radiology on behalf of a well-established, physician-led radiology practice seeking talented professionals to join their team. This client offers a modern, suppo...

United States
Wheel logo

Nurse Practitioner

Wheel

The virtual care platform for delivering consumer-centric care

Medical Director2 days ago
ContractRemoteTeam 201-500Since 2018H1B Sponsor

Wheel Medical Group is seeking nurse practitioners with multiple state licenses to join our network of world-class clinicians delivering virtual care. Wheel Medical Group offers a better way to work in virtual care by enabling clinicians to work with multiple telehealth companies...

United States