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Adaptive Biotechnologies Corp.

Every immune system has a story to tell; the key is knowing how to listen.

Senior Machine Learning Scientist

Machine Learning EngineerMachine Learning EngineerFull TimeRemoteSeniorTeam 501-1,000Since 2009H1B No SponsorCompany SiteLinkedIn

Location

United States

Posted

3 days ago

Salary

$144.6K - $217K / year

Seniority

Senior

Postgraduate Degree5 yrs expExperience acceptedEnglishPythonPyTorch

Job Description

• Design, implement, train, and iterate on novel deep learning models for TCR–pMHC specificity prediction. • Extend and adapt advances in protein language models, structure prediction, generative modeling, and representation learning to the immune receptor setting. • Utilize scalable training infrastructure to support large-scale model development and experimentation. • Conduct rigorous benchmarking and evaluation strategies to ensure models are scientifically sound and practically superior. • Translate biological principles of T cell recognition into principled modeling decisions. • Influence large-scale experimental data generation to maximize modeling leverage and long-term performance gains. • Provide input and technical recommendations to broader modeling discussions and roadmap planning. • Work closely with computational biology, immunology, translational, and engineering teams to ensure models are robust, reproducible, and aligned with overall product goals. • Communicate modeling insights, approaches, and results to cross-functional scientific audiences. • Contribute to publications, presentations, etc. through technical execution and analysis.

Job Requirements

  • PhD in a quantitative discipline (e.g. Machine Learning, Computational Biology, Computer Science) + 5 years progressive experience applying machine learning to real-world scientific or biological problems OR equivalent combination of education and experience.
  • Progressive experience in the development and deployment of deep learning methods
  • Strong hands-on experience in python and modern ML tooling (PyTorch preferred)
  • Strong experience in deep learning architecture design and implementation.
  • Experience working with large datasets and high-performance computing environments
  • Ability to independently define, scope, and execute complex technical research problems.
  • Strong written and verbal communication skills, with ability to present highly technical material to diverse audiences.
  • Demonstrated ability to collaborate effectively in cross-functional, multi-disciplinary teams
  • Driven by impact: motivated to see models transition from research to clinical and commercial application.

Benefits

  • equity grant
  • bonus eligible

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