• Execute and oversee centralized monitoring activities across clinical trials using a risk-based quality management (RBQM) framework • Perform ongoing centralized monitoring reviews using clinical, operational, and quality data sources • Identify emerging study-level and site-level risks through Key Risk Indicators (KRIs) • Support the evaluation of trends, data anomalies, and protocol deviations • Document and report signals, findings, and recommendations within designated systems • Collaborate with Clinical Monitoring to support alignment of monitoring approaches with ICH-GCP E6 (R2/R3) and internal SOPs • Support oversight of centralized monitoring vendors, tools, or platforms • Participate in ongoing improvements in standardizing technologies, systems, processes, and training materials