We are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Staff Machine Learning Scientist
Location
United States
Posted
5 days ago
Salary
Not specified
Job Description
Role Description
Natera is seeking a Staff Machine Learning Scientist – Translational AI to provide technical leadership at the intersection of biomedical foundation models, computational biology, and clinical translation. This role is responsible for shaping how genomic, pathology and multimodal foundation models are applied to high-impact translational problems, including:
- Target identification
- Drug and biomarker discovery
- Patient stratification
- Therapeutic development
As a Staff-level scientist, you will operate with broad technical autonomy, influencing modeling strategy across multiple initiatives while remaining hands-on in model development, experimentation, and interpretation. You will work closely with AI scientists, translational scientists, bioinformatics, clinical partners, and ML engineers to ensure foundation models deliver biologically grounded and clinically meaningful insights.
Qualifications
- PhD in Computational Biology, Bioinformatics, Computer Science, or a related quantitative field.
- 5+ years of experience applying ML to biological, genomic, or clinical data, in the field of oncology, immunology, or translational medicine.
- Deep experience with foundation models, representation learning, self-supervised learning, or deep sequence models.
- Demonstrated ability to translate ML outputs into biological insight or clinical value, not just metrics.
- Strong proficiency in PyTorch and modern ML tooling (e.g., HuggingFace transformers, PEFT, Captum, MLFow).
- Track record of scientific and technical leadership through project ownership, mentorship, or cross-team influence.
Requirements
- Experience integrating genomics with imaging or clinical data in multimodal foundation models.
- Experience with drug discovery, clinical trial data, real-world evidence, or regulatory-facing analyses.
- Strong publication record in ML, computational biology, or translational research venues.
Benefits
- Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Free testing for Natera employees and their immediate families, in addition to fertility care benefits.
- Pregnancy and baby bonding leave.
- 401k benefits.
- Commuter benefits.
- Generous employee referral program.
Company Description
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
Job Requirements
- PhD in Computational Biology, Bioinformatics, Computer Science, or a related quantitative field.
- 5+ years of experience applying ML to biological, genomic, or clinical data, in the field of oncology, immunology, or translational medicine.
- Deep experience with foundation models, representation learning, self-supervised learning, or deep sequence models.
- Demonstrated ability to translate ML outputs into biological insight or clinical value, not just metrics.
- Strong proficiency in PyTorch and modern ML tooling (e.g., HuggingFace transformers, PEFT, Captum, MLFow).
- Track record of scientific and technical leadership through project ownership, mentorship, or cross-team influence.
- Experience integrating genomics with imaging or clinical data in multimodal foundation models.
- Experience with drug discovery, clinical trial data, real-world evidence, or regulatory-facing analyses.
- Strong publication record in ML, computational biology, or translational research venues.
Benefits
- Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
- Free testing for Natera employees and their immediate families, in addition to fertility care benefits.
- Pregnancy and baby bonding leave.
- 401k benefits.
- Commuter benefits.
- Generous employee referral program.
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