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Portfolio and Business Operations Lead
Location
United States
Posted
5 days ago
Salary
$220K - $350K / year
No structured requirement data.
Job Description
Role Description
The Portfolio and Business Operations Lead will drive strategic planning, operational excellence, and resource optimization for a high-impact pre-clinical portfolio within a dynamic research environment. This role translates broad organizational strategies into actionable initiatives that accelerate early clinical development, while overseeing portfolio performance and cross-functional resource allocation. You will partner closely with senior leadership to enable data-driven decisions, maintain stakeholder alignment, and implement robust governance frameworks. This position requires strategic insight, analytical rigor, and strong communication skills to support innovation-driven programs and high-performing teams. The role offers an opportunity to influence global operations while working in a collaborative, matrixed environment focused on delivering meaningful value to patients.
- Drive strategic planning and execution for the pre-clinical portfolio, focusing on early clinical development initiatives.
- Monitor portfolio performance, risks, milestones, and key metrics to inform timely, data-driven decisions.
- Lead cross-functional resource planning and allocation to ensure successful delivery of portfolio objectives.
- Manage stakeholder alignment across leadership, cross-functional teams, and governance bodies.
- Track deliverables and integrate portfolio frameworks, including governance, milestones, and RACIs.
- Support the translation of strategy into actionable initiative roadmaps, including analytics, working sessions, and strategic communications.
- Oversee talent development, succession planning, and high-performance culture initiatives within the portfolio team.
Qualifications
- Advanced academic or strategic background (MD, PhD, MBA) with at least 10 years of relevant experience in pharmaceuticals, biotech, or consulting, ideally in inflammation or related therapeutic areas.
- Proven experience leading change, implementing business/process/system improvements, and driving operational excellence.
- Strong portfolio and project management expertise with deep knowledge of early clinical development and PoC strategies.
- Demonstrated leadership in complex, global matrix organizations with the ability to influence senior stakeholders.
- Exceptional analytical skills, including performance assessment and decision-support insights.
- Executive-ready communication skills and high digital literacy to advocate data- and technology-enabled approaches.
- Compliance-focused mindset aligned with high-quality standards and regulatory requirements.
Benefits
- Competitive base salary range: $220,000 – $350,000.
- Role-specific discretionary bonus and potential relocation support.
- Comprehensive benefits package including medical, dental, vision, and life insurance.
- Retirement plans and contribution programs.
- Paid time off and vacation policies to support work-life balance.
- Professional development opportunities and a collaborative, innovation-driven environment.
Job Requirements
- Advanced academic or strategic background (MD, PhD, MBA) with at least 10 years of relevant experience in pharmaceuticals, biotech, or consulting, ideally in inflammation or related therapeutic areas.
- Proven experience leading change, implementing business/process/system improvements, and driving operational excellence.
- Strong portfolio and project management expertise with deep knowledge of early clinical development and PoC strategies.
- Demonstrated leadership in complex, global matrix organizations with the ability to influence senior stakeholders.
- Exceptional analytical skills, including performance assessment and decision-support insights.
- Executive-ready communication skills and high digital literacy to advocate data- and technology-enabled approaches.
- Compliance-focused mindset aligned with high-quality standards and regulatory requirements.
Benefits
- Competitive base salary range: $220,000 – $350,000.
- Role-specific discretionary bonus and potential relocation support.
- Comprehensive benefits package including medical, dental, vision, and life insurance.
- Retirement plans and contribution programs.
- Paid time off and vacation policies to support work-life balance.
- Professional development opportunities and a collaborative, innovation-driven environment.
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