REPORTING TO: Senior Vice President Finance and Administration Finance

LOCATION: Corporate Headquarters currently located in Irvine, California or remote from the Employee’s home office

SALARY BAND: $215,000-$225,500 with a 20% target bonus. Final compensation will be commensurate with the candidate’s experience, education, skills, and overall alignment with the role’s requirements.

EQUITY GRANT ELIGIBLE: Yes

POSITION SUMMARY:

Reporting to the Senior Vice President Finance and Administration Finance, the Director Financial Planning & Analysis (“FP&A”) will play a critical role in driving financial strategy, operational performance, and long-term value creation for Ambros Therapeutics, Inc. (“Ambros” or the “Company”). This individual will be responsible for leading corporate financial planning, budgeting, forecasting, and strategic analysis to support executive decision-making across clinical, research, and corporate functions.

This is an individual contributor role initially and may grow into future leadership responsibilities as the Company scales toward public-company readiness. The ideal candidate will be a dynamic, experienced, execution-focused leader who can foster strong collaboration with business partners. The role requires exceptional financial acumen, analytical rigor, strong leadership insight and communication, and the ability to translate complex data into actionable insights. Success in this position requires strong communication and organizational skills, professionalism, sound judgment, and the ability to operate effectively in a fast-paced, evolving biotech environment.

ESSENTIAL DUTIES AND RESPONSIBILITIES

• Lead company-wide financial planning processes, including annual budgets, long-range plans, and rolling forecasts.
• Partner with executive leadership and functional heads (Research and Development (“R&D”), Clinical, Regulatory, Commercial, and General and Administrative (“G&A”)) to develop and manage operating plans, drive operational decisions, and resource allocation.
• Drive financial modeling to support strategic initiatives, pipeline investments, clinical development scenarios, and capital planning.
• Contribute to Board of Directors and investor reporting, including preparation of financial presentations, performance analysis, and key metrics.
• Ensure financial discipline through variance analysis, expense tracking, and performance monitoring across departments.
• Drive additional rigor in R&D investments, and adoption of program-level reporting and planning - including clinical trial costs.
• Ensure close collaboration with accounting and other teams to ensure alignment of actual results and forecasts and to support month-end close and financial reporting.
• Lead FP&A financial system implementations and integrations.
• Review and contribute to financing strategies, fundraising support, and scenario planning related to capital requirements and runway management.

MINIMUM EXPERIENCE, EDUCATION, CERTIFICATIONS, & LICENSES:

• Bachelor’s degree in Finance, Accounting, Economics, or related field required; MBA, CPA, or CFA is strongly preferred.
• Minimum of 10+ years of progressive experience in financial planning and analysis, with at least 3–5 years in the biotechnology, pharmaceutical, or life sciences industry.
• Strong experience in corporate financial planning, forecasting, and strategic modeling in a growth-stage or publicly traded environment.
• Proven track record of supporting executive leadership with data-driven insights and strategic recommendations.
• Demonstrated integrity, accountability, and commitment to financial transparency and operational excellence.

SKILLS & QUALIFICATIONS:

• Strategic thinker with strong analytical and problem-solving capabilities and an entrepreneurial mindset suited to a startup environment.
• Superior verbal, written, and presentation communication skills, with the ability to influence senior leadership and cross-functional stakeholders.
• Excellent leadership skills with demonstrated ability to manage/collaborate across scientific, clinical, and corporate functions.
• Deep expertise in financial modeling, scenario analysis, budgeting, and performance management.
• Strong understanding of biotech business drivers, including clinical development timelines, pipeline investment decisions, and capital planning.
• Demonstrated ability to prioritize competing demands and operate effectively with minimal supervision in a rapidly changing environment.
• Knowledge of internal controls, financial governance, and compliance standards relevant to the biotechnology industry.
• Ability to assess financial risks, evaluate impact on corporate strategy, and support timely decision-making.
• Ability to interpret complex financial and operational data, prepare executive-level reports, and communicate insights clearly.
• Upholds high ethical standards and maintains integrity in all activities.
• Proficient with financial planning systems, enterprise resource planning tools, and Microsoft Office Suite.

WORK LOCATION AND TRAVEL REQUIREMENTS:

This position is based from an Ambros corporate office or remote from the Employee’s home office, subject to Company policy and business needs. If remote, a dedicated home office space that is professional in appearance, quiet, and secure where confidential conversations can occur and a high-quality high-speed internet connection are required.

Regardless of primary work location, the role requires in-person presence approximately once per month for multi-day meetings at the corporate headquarters or other designated locations, as determined by business or department priorities.

Occasional domestic travel is required, including overnight stays. Travel expectations may reach up to 10%, depending on operational priorities and Company needs.

PHYSICAL REQUIREMENTS & ENVIRONMENTAL CONDITIONS: This position is primarily performed in a professional office or home-office setting.

With or without reasonable accommodation, the employee must be able to:

• Operate a computer and standard office equipment;
• Communicate effectively in person, via telephone, and through video conferencing platforms;
• Travel independently, including overnight and international trips, and travel by personal vehicle and transit systems; and
• Navigate office environments and other professional settings.

Additional requirements include:

• Prolonged periods of sitting, standing, and walking;
• Occasional lifting or carrying of items up to 20 pounds;
• Ability to read, comprehend, and apply policies, procedures, and regulations written in English;
• Ability to write clear, factual, and grammatically correct communications and reports in English; and
• Ability to use logic and data for problem-solving and to exercise sound judgment.

EQUAL EMPLOYMENT OPPORTUNITY

As an equal opportunity employer, Ambros is committed to providing all applicants and employees with equal access to employment opportunities, regardless of sex, race, age, color, national origin, ancestry, disability, pregnancy, religion, genetic information, sexual orientation, transgender status, gender identity, marital status, military or veteran status, or any other characteristic protected by applicable law. All employees, officers, and representatives of Ambros are expressly prohibited from engaging in unlawful discrimination, harassment, or retaliation.

Consistent with all applicable requirements, Ambros will reasonably accommodate any qualified individual with a disability if such accommodation would allow the individual to perform the essential functions of the job, unless doing so would create an undue hardship on the Company.

Ambros also follows all applicable federal, state, and local laws governing work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and Immigration Reform and Control Act. Ambros is an E-Verify employer.