Natera
We are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.
Principal Architect – ECD
Location
United States
Posted
63 days ago
Salary
$182.9K - $228.6K / year
Bachelor Degree12 yrs expEnglishAWSCloud
Job Description
• Define and own architectural strategy across product lines, ensuring alignment with long-term technical and business goals.
• Design and evolve cloud-native systems with a focus on scalability, maintainability, observability, and security.
• Create architectural blueprints and reusable frameworks that guide teams in building high-performance services and user-facing applications.
• Act as a technical thought partner to engineering leadership, product managers, and executive stakeholders.
• Mentor senior engineers and architects, cultivating a culture of system thinking and technical excellence.
• Drive architectural governance, setting standards, conducting reviews, and managing risk across projects.
• Lead modernization initiatives, including migration from monolithic to service-oriented or event-driven architectures.
• Evaluate and introduce emerging technologies that improve developer productivity and system resilience.
• Partner with AI/ML teams to ensure scalable integration of intelligent services and real-time analytics.
• Work closely with teams to guide solution design, decomposition, and trade-off decisions.
• Support high-priority projects through planning, hands-on design sessions, and technical troubleshooting.
• Maintain a system-level view of infrastructure, services, and data flows to anticipate bottlenecks and scale risks.
Job Requirements
- 12+ years of professional software engineering experience, with 6+ years in a senior architectural leadership role.
- Deep experience designing and scaling enterprise software systems, particularly in cloud-native environments (AWS preferred).
- Proven success with architectural transformation initiatives (e.g., service decomposition, domain-driven design, platform re-architecture).
- Strong understanding of architectural trade-offs in system design (performance, resilience, cost, etc.).
- Excellent communication skills with the ability to explain complex technical concepts to both technical and non-technical audiences.
- Experience with scientific, healthcare, or lab operations domains (preferred).
- Familiarity with LIMS/LES systems, AI integration patterns, or regulated software environments (preferred).
Benefits
- Annual performance incentive bonus
- Long-term equity awards
- Comprehensive health benefits (medical, dental, vision)
- 401(k) with company match
- Generous paid time off and company holidays
- Additional wellness and work-life benefits
Related Guides
Related Categories
Related Job Pages
More Architect Jobs
Architect63 days ago
Full TimeRemoteTeam 1-10H1B No Sponsor
SAP TM Integration Architect designing complex logistics integrations
CloudSOAP
United States
Domain Architect
LaterLevel up your social media marketing strategy ✨ Schedule, plan, engage & grow 🌴
Architect64 days ago
Full TimeRemoteTeam 51-200Since 2014H1B Sponsor
Domain Architect leading platform architecture for social media software.
AWS
Project Architect V – Healthcare
CannonDesignWe design solutions that help people continuously flourish. Living-Centered Design is how we do it.
Architect64 days ago
Full TimeRemoteTeam 1,001-5,000H1B No Sponsor
Project Architect responsible for leading technical aspects in healthcare design
Regional Manager, Architecture & Engineering
Axis CommunicationsInnovating for a smarter, safer world.
Architect65 days ago
Full TimeRemoteTeam 1,001-5,000Since 1984H1B No Sponsor
Architect & Engineer Regional Manager managing A&E relationships for Axis Communications