• Oversee the ISS review and approval process, including proposal validation, coordination of reviews, and communication of decisions to stakeholders. • Manage the MAP/PTA review and approval process, including coordination of case reviews, decision documentation, and communication with relevant parties. • Serve as the global point of contact for ISS and MAP management for designated products, working with cross-functional internal and external stakeholders. • Maintain comprehensive databases for ISS and MAP/PTA, tracking proposals, studies, and decisions with relevant documentation. • Facilitate contract development and negotiation between sponsors/requestors and Sobi, collaborating with legal, MPL, and other functions as required. • Support supply chain set-up in conjunction with Affiliate teams and Sobi Supply Chain for both ISS and MAP/PTA programs. • Provide regular status updates on ISS and MAP/PTA programs to responsible teams and leadership. • Monitor milestone payments and report ISS budget to budget owners. • Coordinate with vendors on the set-up and management of MAP and PTA programs as needed.