• Play a critical leadership role in driving strategic alignment, operational excellence, and execution discipline across Definium’s portfolio of clinical and research programs • Oversee the integrated program management function and ensure that portfolio decisions are data-driven, risk-aware, and aligned with corporate goals • Partner closely with the CEO, CMO, CFO, asset strategy leads, and functional heads to set priorities and track resource allocation • Build and lead a high-performing program management team responsible for the planning, coordination, and execution of development programs • Ensure cross-functional alignment, transparency, and accountability across clinical, regulatory, CMC, and commercial readiness functions • Oversee integrated project plans, timelines, milestones, and budgets • Interface with key external partners to integrate external project management with internal cross-functional teams • Establish best practices, tools, and templates for program governance, reporting, and performance tracking • Provide regular program and portfolio updates to executive leadership and the Board of Directors • Partner with Finance and Strategy functions on long-range planning and external communications