• Develop and maintain forecasts for pipeline assets including assumptions, methodologies, and documentation. • Assess forecast risk and uncertainty, run sensitivities analysis and scenarios. • Conduct primary and secondary market research to understand disease epidemiology, patient segmentation, treatment paradigm, unmet medical needs, competitive landscape, etc. • Translate insights from market research to both qualitative and quantitative commercial assessment. • Support major planning processes such as LRP, portfolio prioritization and other strategic planning cycles with forecast submissions, scenarios, and narratives. • Coordinate inputs and data from internal sources and external datasets; ensure data quality and consistent use of definitions/assumptions across teams. • Provide commercial/business case assessment to inform pipeline programs’ go-no-go and critical investment decisions. • Present and defend commercial cases in front of senior leadership. • Collaborate with cross-functional teams to establish Target Product Profiles and develop market positioning strategies for early-stage pipeline programs. • Collaborate with cross-functional teams to establish relevant Disease Area Strategies.